Preparation of quercetin glucuronides and characterization by HPLC-DAD-MS/MS

DUEÑAS M., SANTOS-BUELGA C.; MINGO-CHORNET H; PÉREZ-ALONSO J. J.; DI PAOLA-NARANJO R.; GONZÁLEZ-PARAMÁS A. M.; SANTOS-BUELGA C.

SPRINGER

Año: 2008 vol. 227 p. 1069 - 1069

p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; LINE-HEIGHT: 150%; TEXT-ALIGN: justify">Quercetin is the main flavonol in the human diet, and the most commonly used in studies of biological activity. The major circulating forms of quercetin found in the human plasma after consumption of food containing distinct quercetin glycosides are glucuronides and sulfates. In this work quercetin glucuronides have been obtained from green beans (quercetin 3-glucuronide) and by enzymatic synthesis (quercetin 4?-glucuronide) using a modification of the method described by Plumb et al.(1)