Heat killed cells of Cryptococcus neoformans var. grubii

JOSE´ L. BARONETTI, LAURA S. CHIAPELLO, MARI´A P. AOKI, SUSANA GEA & DIANA T. MASIH

MEDICAL MYCOLOGY

Taylor and Francis

Año: 2006 vol. 44 p. 493 - 493

1369-3786

font face="AdvTR" size="3"> Different clinical parameters which included cell-mediated immune (CMI) response, were evaluated in a model of disseminated cryptococcosis in rats. The experimental animals were pretreated four days prior to their exposure to Cryptococcus neoformans var. grubii with either heat killed cells of this yeastlike pathogen (HKC) or capsular polysaccharide (CPS) emulsified in complete Freund adjuvant (CFA). Rats treated with HKC-CFA and intraperitoneally infected withvar. grubii with either heat killed cells of this yeastlike pathogen (HKC) or capsular polysaccharide (CPS) emulsified