What can we learn about amphiphile-membrane interaction from model lipid membranes?

FANANI, M. LAURA; NOCELLI, NATALIA; ZULUETA DÍAZ, YENISLEIDY DE LAS MERCEDES

Virtual

Congreso; 1st Symposium on Colloid and Interface Science; 2021

comunidad mexicana de materia blanda condensada

Surface-active amphiphiles find applications in a wide range of areas of industry such as agrochemicals, personal care, and pharmaceuticals. In many of these applications, interaction with cell membranes is a key factor for achieving their purpose. How do amphiphiles interact with lipid membranes? What are their bases for membrane specificity? Which biophysical properties of membranes are susceptible to modulation by amphiphilic membrane-effectors? What aspects of this interaction are important for performing their function? In our work on membrane biophysics over the years, questions like these have arisen and we now share some of our findings and discuss them with the aim to deeper understand the modes of action of amphiphiles of biological interest..