Amperometric biosensor for the quantification of gentisic acid using polyphenol oxidase modified carbon paste electrode

M. L. PEDANO ; G. A. RIVAS

ELSEVIER SCIENCE BV

Año: 2000 vol. 53 p. 485 - 485

font size="1" face="TimesNRMT"> The affinity of mushroom polyphenol oxidase (PPO) towards gentisic acid (GA), a metabolite of acetyl salicylic acid (ASA), is demonstrated by spectrophotometry and by electrochemical techniques. The enzyme can selectively recognize GA even in the presence of large excess of ASA and its metabolic derivatives (salicylic acid (SA) and salicyluric acid (SUA)). At 0.150 V, the sensitivity is (6.190.1)¡¡10