Glucose Biosensor Based on the Immobilization of Glucose Oxidase and Polytyramine on Rhodinized Glassy Carbon and Screen Printed Electrodes

S. A. MISCORIA; G. D. BARRERA; G. A. RIVAS

Sensors and Actuators B

Elsevier

Año: 2006 vol. 115 p. 205 - 205

b> Abstract This work reports on a new amperometric glucose biosensor based on the modification of glassy carbon and screen printed electrodes with rhodium as catalyst, glucose oxidase (GOx) as biorecognition element, and in situ electrogenerated polytyramine as anti-interferents barrier. The excellent electrocatalytic activity of rhodium makes possible a huge enhancement in the oxidation currents of the hydrogen peroxide enzymatically generated from glucose. The polytyramine layer largely improves the selectivity of such response. No interference is observed even for large excess of ascorbic acid, uric acid and acetaminophen. A fast response (5 s) is obtained at the glassy carbon electrode modified with rhodium, glucose oxidase and polytyramine, with a linear relationship between current and glucose concentration up to 1.50×