Carbon nanotubes-based electrochemical (bio)sensors for biomarkers

RIVAS, G; M. C. RODRÍGUEZ; RUBIANES M. D.,; GUTIERREZ F.; MARCOS EGUILAZ,; DALMASSO P.; E. PRIMO; TETTAMANTI, C. S.; RAMÍREZ, M. L; ANTONELLA MONTEMERLO,; PABLO GALLAY; CONCEPCION PARRADO

Applied Materials Today

Elsevier

Año: 2017 vol. 9 p. 566 - 566

2352-9407

his review is focused on the critical discussion about the most representative carbon nanotubes(CNTs)-based electrochemical (bio)sensors for the quantification of different biomarkers of clinicalrelevance reported in the period 2013?2017 (carcynoembryonic antigen, prostate specificantigen, alpha-fetoprotein, cytokines, cardiac biomarkers, insulin growth factor-1, -galactoside--2,6-sialyltransferase, DNA sequences, microRNAs, and dopamine). We concentrated our attention on themolecules used as (bio)recognition elements, the approaches for immobilizing these (bio)recognitionmolecules at the electrode surfaces, the strategies to generate the analytical signal (label-free or labeled),the analytical performance of the resulting (bio)sensors, and the role of CNTs in these different aspects.