Carbon nanomaterials-based cancer biomarkers electrochemical biosensors

MARCELA C. RODRÍGUEZ; DALMASSO P.; M. DOLORES RUBIANES; BOLLO, SOLEDAD; GALLAY, PABLO; LÓPEZ MUJICA, MICHAEL; ANTONELLA MONTEMERLO; PERRACHIONE FABRIZIO; TAMBORELLI, LUIS A.; VASCHETTI VIRGINIA; DIANA REARTES; G. A. RIVAS; SIBEL OZKAN; NURGUL BAKIRHAN; FARIBA MOLLARAOSOULI

The detection of biomarkers: past, present and the future prospects

Elsevier

Año: 2022;

This chapter presents a critical discussion about the most relevant carbon nanomaterials-based electrochemical biosensors for the quantification of typical cancer biomarkers like microRNAs, prostate-specific antigen, alpha-fetoprotein, and carcinoembryonic antigen reported in the period 2015?20. The analysis is focused on the strategies used to build the biosensing platforms, from the selection and immobilization of the biorecognition element, to the transduction of the bioaffinity event into a measurable signal, with special emphasis on the analytical characteristics of the resulting biosensors