Fighting Antimicrobial Resistant Microorganisms: Current Status and Emerging Strategies Using Nanomaterials

PARAJE MG; PÁEZ PL

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY

FRONTIERS MEDIA S.A

Año: 2021

2296-4185

ntimicrobial resistance is a global crisis and, along with the availability of few effective antimicrobials, emphasize the need for new approaches and different safe and effective alternatives to current antimicrobials strategies. Recent progress in biomedical applications has been proposed to prevent or treat resistant pathogens due to the limited efficacy of antimicrobial agents. Metal nanoparticles (NPs) are attracting huge interest in nanobiology and nanomedicine fields as a new class of antimicrobial agents, because of their ease of preparation, their high stability over time, and lower probability of developing resistance by microorganisms. In the past 2 decades, NPs have received attention as a potential future treatment of a wide range of serious infections. Particularly metal NPs are considered promising due to their unique physicochemical properties, chemical composition, size, surface charge, and similar size to intra- and extra-cellular components that allow specifically i