Artículos
Título:
Potential use of ascorbic acid based surfactants as skin penetration enhancers
Autor/es:
SANTIAGO PALMA,; BELKYS MALETTO,; LO NOSTRO, PIERANDREA; RUBEN MANZO,; PISTORESI PALENCIA, CRISTINA; DANIEL ALBERTO ALLEMANDI
Revista:
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
Editorial:
Informa Healthcare
Referencias:
Año: 2006 vol. 32 p. 1 - 1
Resumen:
p class="MsoTitle" style="MARGIN: 0cm 0cm 0pt; TEXT-ALIGN: justify">6-O-Ascorbic acid alkanoates (ASCn) are amphiphilic molecules having physical-chemical properties that depend on the alkyl chain length. The derivatives of low molecular weight (n<11) have enough aqueous solubility to produce self-assemblies at room temperature (?25ºC), while those with longer alkyl chains possess a critical micellar temperature (CMT) higher than 30ºC. At hig