Rheological and tensile properties of sodium hyaluronate hydrogels and films.

CALLES J.; RESSIA J.; LLABOT J.; PALMA S; ALLEMANDI D; VALLES E

Córdoba

Congreso; Primera Reunion Internacional de Ciencias Farmacéuticas – RICiFa; 2010

Grupo Farmacotecnia. FCQ-UNC

HA is distributed in the human body forming part of synovial fluid, skin, umbilical cord and vitreous humor; and widely used in medical practice in many pathological conditions such as osteoarthritis, wound repair and eye surgery (1-5). Several studies related to biocompatibility and biodegradability (6) have suggested the use of HA as a promising biomaterial to design modified drug delivery systems with ophthalmic applications. In this work we present preliminary studies in order to evaluate rheological and mechanical properties of hydrogels and films based on HA prior to further structural modification needed to improve the biomechanical properties of HA.