Immunization with crude antigens plus aluminium hydroxide protects cattle from Fasciola hepatica infection

GUASCONI, L.; SERRADELL, M.C.; BORGONOVO, J.; GARRO, A.P.; VARENGO, H.; CAFFE, G. AND MASIH, D.T.

CAMBRIDGE UNIV PRESS

Año: 2011 vol. 3 p. 1 - 1

p style="TEXT-ALIGN: justify; LINE-HEIGHT: 200%; MARGIN: 0cm 0cm 0pt" class="MsoNormal">Abstract The ability of total homogenate (TH) of Fasciola hepatica conjugated with aluminium hydroxide (alum) or Freund´s complete adjuvant (FCA) to protect cattle against experimental fasciolosis was evaluated. Compared with the infected group, the immunized animals with alum-TH and FCA-TH presented a significant reduction in fluke burden (85.9% and 96.8% respectively), a higher p