LUQUE GUILLERMINA LETICIA
Artículos
Título:
Electrochemical sensor for amino acids and albumin based on composites
Autor/es:
EMILIANO N. PRIMO, FABIANA GUTIERREZ, PABLO DALMASSO, AURELIEN GASNIER, MARCOS EGUILAZ, GUILLERMINA L. LUQUE, MARÍA L. PEDANO, MARCELA C. RODRÍGUEZ, NANCY F. FERREYRA, MARÍA D. RUBIANES, GUSTAVO A. RIVAS; NANCY F. FERREYRA; GUSTAVO A. RIVAS
Referencias:
Año: 2007 vol. 71 p. 1282 - 1282
Resumen:
his work reports on the analytical performance of composites obtained by dispersing copper microparticles and multi-wall carbon nanotubes
within a mineral oil binder (CNTPE-Cu) for the determination of amino acids and albumin. The strong complexing activity of amino acids towards
copper makes possible an important improvement in the sensitivity for the determination of amino acids and albumin. This new electrode permits
the highly sensitive amperometric detection of amino acids, even the non-electroactive ones, at very low potentials (0.000 V) and physiological
pH (phosphate buffer solution pH 7.40). The response of the electrode is highly dependent on the amount of copper, demonstrating the crucial
role of the metal in the analytical performance of the sensor. The best analytical performance is obtained for the electrode containing 6.0% (w/w)
copper. The resulting sensor shows a fast response (7 s) and a sensitivity that depends on the nature of the amino acid. The electrode su