Specific binding capacity of B-ciclodextrin with cis and trans enalapril: Physicochemical characterization and structural studies by molecular modeling

ARIANA ZOPPI; MARIO A. QUEVEDO; MARCELA R. LONGHI

Elsevier Science

Año: 2008 vol. 16 p. 8403 - 8403

font size="1" face="AdvGulliv-R"> The main objective of this work was to study an inclusion complex between enalapril (ENA), and B-cyclodextrin (B-CD). From nuclear magnetic resonance (NMR) we determined that the complex showed a 1:1 stoichiometry, with an apparent formation constant (KC) of 439 and 290 M1 for the