Syntheses of phenanthridines and benzophenanthridines by

MARIA E. BUDÉN

TETRAHEDRON LETTERS

Elsevier

Lugar: Orlando- USA; Año: 2007 vol. 48 p. 8739 - 8739

0040-4039

he photostimulated reaction of N-(2-halo-benzyl)aryl amines with t-BuOK in liquid ammonia affords fused azaheterocycles by the SRN1 mechanism. The starting materials are easily obtained by the reaction of 2-halo-benzyl chloride and aromatic amines to prepare the secondary amines. Through this approach, phenanthridine (90%), 4-phenylphenanthridine (87%), benzo[a]phenanthridine (98%), and benzo[c]phenanthridine (84%) were synthesized.