Oxidation of organosulfur compounds promoted by continuous-flow chemistry

COLOMER, JUAN PABLO; TRAVERSSI, MIQUEAS; OKSDATH-MANSILLA, GABRIELA

Journal of Flow Chemistry

Springer International Publishing

Año: 2020 vol. 10 p. 123 - 123

2062-249X

rganosulfur compounds are important moieties found in several medicinal drugs used in the therapy of arthritis, cancer, depression, diabetes or immune deficiency syndrome. Furthermore, organosulfur compounds are intermediates in many organic reactions with a key role as ligands or chiral auxiliaries. Due to their importance in various areas as pharmaceutical chemistry, synthetic organic chemistry, as well as materials science, the development of new and more sustainable synthetic protocols to provide access to different organosulfur compounds, has a high impact on the broader chemistry community. Many interesting transformations of organosulfur compounds involve an oxidation reaction to access to organosulfur derivatives such as disulfide, sulfinyl or sulfones. Organosulfur oxidation is typically carried out using different oxidant agents such as peroxides, peracids or using atmosphere oxygen under photocatalysis. Despite the numerous procedures reported in the academia, the developme