Pros and cons of coating layered double hydroxide nanoparticles with polyacrylate

VASTI, CECILIA; GIACOMELLI, CARLA E.; ROJAS, RICARDO

APPLIED CLAY SCIENCE

ELSEVIER SCIENCE BV

Año: 2019 vol. 172 p. 11 - 11

0169-1317

reventing the aggregation of layered double hydroxide nanoparticles (LDH-NP) and producing additional functionality are two important objectives for their applications as drug nanocarriers, among others. Adsorption of polyelectrolytes like polyacrylate (PA) is a promising approach to produce protective, functional coatings, but the effect of factors such as chain length, as well as the pros and cons of this strategy, have not been described. In this work, these aspects were studied using LDH-NP intercalated with chloride and benzoate as interlayer probes. The interaction between LDH-NP and PA, as well as the effect in the aggregation of the former, was studied as a function of the molecular weight (MW = 1.2, 8.0 and 450 kDa) and the PA concentration. High MW were more effective for preventing LDH-NP aggregation as well as for minimizing the PA intercalation between the layers. Thus, the 8.0 kDa PA allowed obtaining benzoate intercalated LDH-NP with a particle s