Highly Stable Graphene Oxide-Gold Nanoparticle Platforms for Biosensing Applications

HERNÁNDEZ-SÁNCHEZ, DANIA; VILLABONA LEAL, EDGAR GIOVANNY; SAUCEDO-OROZCO, IZCOATL; BRACAMONTE, VICTORIA; PÉREZ, ELÍAS; BITTENCOURT, CARLA; QUINTANA, MILDRED

PHYSICAL CHEMISTRY CHEMICAL PHYSICS

ROYAL SOC CHEMISTRY

Lugar: CAMBRIDGE; Año: 2017

1463-9076

raphene oxide-gold nanoparticle (AuNP@GO) hybrids were fabricated in water dispersions of graphene oxide (GO) and Au precursor completely free of stabilizing agents by UV-light irradiation. Gold nanoparticles (AuNP) nucleation, growth, and stabilization mechanisms at the surface of GO are discussed on the basis of UV-Vis, Raman, IR, and X-Ray photo-spectroscopy studies. The analyses of AuNP@GO hybrids by transmission electron microscopy (TEM), thermo gravimetric (TGA) and electrochemical tests exhibit outstanding chemical, thermal and electrochemical stabilities. Thus, AuNP@GO biosensing platforms were fabricated for surface enhanced Raman spectroscopy (SERS) detection of Crystal Violet (CV) a SERS standard molecule, and in a different set of experiments, for flavin adenine dinucleotide (FAD) a flavoprotein coenzyme that plays an important role in many oxidoreductase and reversible redox conversions in biochemical reactions. AuNP@GO hybrids synthesized by using UV light irradiation sh