Amoxicillin administration to a patient with infectious mononucleosis. Report of an adverse reaction case

GARCÍA, MÓNICA C; CAVIGLIASSO, JULIETA; GOLA, CAMILA; VALENTÍN, ROCÍO; SEGURO, MARÍA LAURA; ROMAÑUK, CAROLINA

Ibero Latin American Journal of Health System Pharmacy

Organización de Farmacéuticos Ibero-Latinoamericanos

Lugar: Madrid; Año: 2020

oal: To describe a clinical case of a patient treated with amoxicillin (AMX) while he had a viral infection. In this case, medication error (ME) as well as adverse drug reaction (ADR) were detected.Description of the clinical case: A 7-year-old, 23-kg male patient attended to the hospital with the following symptoms: fatigue, fever and swollen lymph nodes. Pharyngitis caused by bacteria was diagnosed and orally administration of AMX 50 mg/kg/day each 8 h was indicated. One day later, the patient returned to the hospital with skin rash throughout the body. An adverse event (AE) was noticed due to an error in the diagnosis, which was corrected and infectious mononucleosis (MI) was detected. AMX was suspended and remission of the rash was observed. A hospital pharmacist performed the imputation using the Naranjo algorithm (score 5-8) and notified to the Sistema Unificado de Farmacovigilancia of Cordoba.Discussion: Proper diagnosis of IM is essential to avoid inappropriate use of antibiot