Advancements in cell membrane camouflaged nanoparticles: A bioinspired platform for cancer therapy

DHAS, NAMDEV; GARCÍA, MÓNICA C. (SHARED FIRST AUTHORSHIP); KUDARHA, RITU; PANDEY, ABHIJEET; NIKAM, AJINKYA NITIN; GOPALAN, DIVYA; FERNANDES, GASPER; SOMAN, SOJI; KULKARNI, SANJAY; SEETHARAM, RAVIRAJA N.; TIWARI, RUCHI; WAIRKAR, SARIKA; PARDESHI, CHANDRAKANTSING; MUTALIK, SRINIVAS

JOURNAL OF CONTROLLED RELEASE

ELSEVIER SCIENCE BV

Año: 2022 vol. 346 p. 71 - 71

0168-3659

he idea of employing natural cell membranes as a coating medium for nanoparticles (NPs) endows man-made vectors with natural capabilities and benefits. In addition to retaining the physicochemical characteristics of the NPs, the biomimetic NPs also have the functionality of source cell membranes. It has emerged as a promising approach to enhancing the properties of NPs for drug delivery, immune evasion, imaging, cancer-targeting, and phototherapy sensitivity. Several studies have been reported with a multitude of approaches to reengineering the surface of NPs using biological membranes. Owing to their low immunogenicity and intriguing biomimetic properties, cell-membrane-based biohybrid delivery systems have recently gained a lot of interest as therapeutic delivery systems. This review summarises different kinds of biomimetic NPs reported so far, their fabrication aspects, and their application in the biomedical field. Finally, it briefs on the latest advances available in this biohyb