Design, Synthesis and Architectures of Hybrid Nanomaterials for Therapy and Diagnosis Applications

MICAELA A. MACCHIONE; CATALINA BIGLIONE; MIRIAM STRUMIA

Polymers

MDPI

Año: 2018 vol. 10 p. 527 - 527

ybrid nanomaterials based on inorganic nanoparticles and polymers are highly interesting structures since they combine synergistically the advantageous physical-chemical properties of both inorganic and polymeric components, providing superior functionality to the final material. These unique properties motivate the intensive study of these materials from a multidisciplinary viewwith the aim of finding novel applications in technological and biomedical fields. Choosing a specific synthetic methodology that allows for control over the surface composition and its architecture, enables not only the examination of the structure/property relationships, but, more importantly, the design of more efficient nanodevices for therapy and diagnosis in nanomedicine. The current review categorizes hybrid nanomaterials into three types of architectures: core-brush, hybrid nanogels,and core-shell. We focus on the analysis of the synthetic approaches that lead to the formation of eachtype of architectu