Modified-release 3D printed tablets: challenges and opportunities based on geometry and materials

REAL, JUAN PABLO; CAMACHO, NAHUEL; BARBERIS, EUGENIA; PALMA, SANTIAGO D

Journal of 3D Printing in Medicine

Future Medicine Ltd

Lugar: Londres; Año: 2018 vol. 2 p. 93 - 93

2059-4755

he oral administration of drugs is the most common route of delivery due to the preference of patients. There arenumerous solid dosage forms (SDFs) that allow a medication to be administered by swallowing, with tablets andcapsules the most commonly used. From the technological point of view and focusing on production at mediumand large scale, tablets have many advantages over capsules because they can be produced at a lower cost in lesstime.The tablets are solid dosage unit dosage forms, obtained by mechanical compression of granules or mixturesof powders with one or more active pharmaceutical ingredients (APIs), with addition, in most cases, of variousexcipients. The shape, size and weight of tablets may vary, but with restrictions derived from the use of punchesand matrices. For this reason, this type of dosage form does not allow for considerable changes in the geometry ofthe tablet, let alone achieving individual dose adjustments for patients.Based on the aforementioned issues, th