Distribution of Telomeric Sequences (TTAGGG) n in Rearranged Chromosomes of Phyllotine Rodents (Cricetidae, Sigmodontinae).

LANZONI CECILIA; LABARONI CAROLINA; NATALIA SUÁREZ; DANIELA RODRIGUEZ; MACARENA L. HERRERA; ALEJANDRO D. BOLZÁN

CYTOGENETIC AND GENOME RESEARCH

KARGER

Lugar: Basel; Año: 2016 vol. 147 p. 247 - 247

1424-8581

hyllotines are sigmodontine rodents endemic to South America with broad genetic variability, Robertsonian polymorphisms being the most frequent. Moreover, this taxon includes a species with multiple sex chromosomes, which is infrequent in mammals. However, molecular cytogenetic techniques have never been applied to phyllotines to elucidate their karyotypic evolution. We studied the chromosomes of 4 phyllotine species using FISH with a pantelomeric probe (TTAGGG)n. Graomys griseoflavus, Eligmodontia puerulus, and E. morgani are polymorphic for Robertsonian translocations, whereas Salinomys delicatus possesses XX/ XY1Y2 sex chromosomes. Telomeric signals were detected at both ends of all chromosomes of the studied species. In S. delicatus interstitial telomeric sequences (ITS) were observed in the 3 major chromosome pairs, which are equidistant from one of the telomeres in these chromosomes. These results suggest that ITS are important in the reshuffling of the highly derived karyotype