The neuroendocrine system as a model to evaluate experimental gene therapy

HEREÑÚ CB,; BROWN OA,; SOSA YE,; MOREL GR,; REGGIANI PC,; BELLINI MJ,; GOYA RG.

BENTHAM SCIENCE PUBL LTD

Lugar: Karachi, Pakistán; Año: 2006 vol. 6 p. 125 - 125

p class="MsoNormal" style="MARGIN: 0cm 0cm 0pt; mso-layout-grid-align: none">Abstract: The implementation of experimental gene therapy in animal models of neurological diseases is an area of growing interest. Although the neuroendocrine system offers unique advantages for the assessment of in vivo gene therapy, little work has been done in this model. Here we review the core of documented studies in which in vivo gene therapy has been implemented in the neuroendocrine system of rodent models. In the hypothalamus, restorative gene therapy has