Albumin nanocarriers,  - irradiated crosslinked, combined with therapeutic drugs for cancer therapy

ALONSO SILVIA DEL V.

CURRENT PHARMACEUTICAL DESIGN.

BENTHAM SCIENCE PUBL LTD

Lugar: Oak Park; Año: 2017

1381-6128

lbumin polymeric Nanoparticles (NPs) have opened a great expectancy as for controlled drug delivery due to their therapeutic potency. Concomitantly biodegradable NPs technologies with target linked structures to pave the way of personalised medicine are becoming increasingly important in sight of a therapeutically effective research technology. This is particularly attractive for nanoparticle-based cancer delivery systems, based on the known limitations and efforts to overcome. This new group of gamma irradiated-NPs, inherited both the protein delivery properties and robustness of polymer forming structures, and gamma irradiation techniques that leaves a clean, innocuous and biodegradable NPs. These protein NPs made up of serum albumin are referred to SA NPs that possesses several characteristics making them especially attractive to be considered as a drug delivery system. This reviews focused on methodologies actually being used in the synthesis and characterization of albumin NPs a