Surface modification on poly (EGDMA-co-HEMA) synthetic matrices to be used as specific adsorbents

CESAR G. GOMEZ; CECILIA I. ALVAREZ IGARZABAL; MIRIAM C. STRUMIA

POLYMER

Elsevier

Año: 2005 vol. 46 p. 6300 - 6300

0032-3861

font face="AdvPS6F00" size="1"> The preparation and modification of ethylene glycol dimethacrylate/2-hydroxyethyl methacrylate copolymers [poly (EGDMA-co- HEMA)] were carried out to study their properties on Immobilized Metal Ion Affinity Chromatography (IMAC). For that purpose, the adsorption–desorption assays of a phosphoprotein, ovalbumin (OVA) on different ion-containing adsorbents were investigated. The metal ion-complexing agent used was iminodiacetic acid (IDA) and the metal ions chelated were Al3C or Fe3C. The efficiency on both modification reactions and OVA retention was analysed taking