Biocomposite films as supports of methylene blue

JESICA CAVALLO; NATALIA ANGEL VILLEGAS; GABRIELA PARAJE; MIRIAM C. STRUMIA; CESAR G. GOMEZ

Córdoba

Workshop; I Reunión Internacional de Ciencias Farmacéuticas (RICIFA); 2010

The synthesis of biocomposite materials obtained from the combination of a natural and a synthetic polymer is being broadly studied, since this type of material displays interesting properties. Biocomposite material has proved useful in such varied fields as biomedical materials, controlled delivery systems, biological tissues engineering and food packaging (1). The biopolymer chitosan is a polysaccharide chemically composed of linkage -(1,4)-2-amino-2-deoxi-D-glucose, it shows attractive properties such as biocompatibility, biodegradability and antimicrobial activity, particularly useful in biomedical material and vegetable conservation (2). On the other hand, methylene blue is a thiazidic dye and it was considered leading compound in clinical areas, including therapeutics for malaria, schizophrenia and cancer. Therefore, this work aimed at attaining biocomposite films based on polypropylene and modified with chitosan as support of methylene blue in order to study the dye activity against the development of Staphylococcus aureus and Escherichia coli.