Imprinting molecular recognition sites in polymer films is an attractive method for the development of biosensors that can cost-effectively test for low abundance analytes. (Figure 1) Currently, even the thinnest films that can be produced are too thick to allow effective mass transfer of analyte to recognition site, limiting practical application of the method. In order to overcome the barriers in traditional membrane manufacturing, we utilize the natural ability of certain molecules to spontaneously aggregate into well-defined architectures on the nanoscale.
For electrochemical biosensors, we are interested in films mounted to electrode surfaces. We have synthesized polystyrene films that are ultra-thin, approximately 3 molecules thick, by using self-assembled bilayers on gold as a removable template for the controlled polymerization of monomers. The films have been characterized by ellipsometry, atomic force microscopy, infrared spectroscopy, and X-ray photoelectron spectroscopy.
For electrochemical biosensors, we are interested in films mounted to electrode surfaces. We have synthesized polystyrene films that are ultra-thin, approximately 3 molecules thick, by using self-assembled bilayers on gold as a removable template for the controlled polymerization of monomers. The films have been characterized by ellipsometry, atomic force microscopy, infrared spectroscopy, and X-ray photoelectron spectroscopy.
For electrochemical biosensors, we are interested in films mounted to electrode surfaces. We have synthesized polystyrene films that are ultra-thin, approximately 3 molecules thick, by using self-assembled bilayers on gold as a removable template for the controlled polymerization of monomers. The films have been characterized by ellipsometry, atomic force microscopy, infrared spectroscopy, and X-ray photoelectron spectroscopy.
For electrochemical biosensors, we are interested in films mounted to electrode surfaces. We have synthesized polystyrene films that are ultra-thin, approximately 3 molecules thick, by using self-assembled bilayers on gold as a removable template for the controlled polymerization of monomers. The films have been characterized by ellipsometry, atomic force microscopy, infrared spectroscopy, and X-ray photoelectron spectroscopy.
