Norovirus passive surveillance as an alternative strategy for genetic diversity assessment in developing countries

DEGIUSSEPPE JUAN; ROITMAN KARINA; RIVERO KARINA; STUPKA JUAN; ARGENTINE NETWORK

Journal of Infection and Public Health

ELSEVIER

Año: 2021 vol. 14 p. 990 - 990

1876-0341

n developing countries, the acute gastroenteritis outbreaks submitted for viral testing are limited dueto deficient surveillance programs. The aim of this study was to analyze a passive surveillance strategyfor monitoring the molecular epidemiology of norovirus (NV) and counterbalance the genetic diversitydata gap.Laboratory-confirmed rotavirus negative sporadic stool samples (N = 523) collected between 2010 and2017 from children were selected from our archival collection and were tested for NV and sequencingwas performed on the positive samples. Passive surveillance information was compared with the geneticdiversity data that was available from local norovirus-confirmed gastroenteritis outbreaks.Each year, norovirus detection in the sporadic samples ranged from 12 to 29%. GI and GII norovirus weredetected in 7 (1.3%) and 101 (19.3%) of the specimens, respectively. Four GI and six GII capsid genotypeswere identified. Six out of 9 strains detected in the NV outbreaks panel were also id