Visual opsins: Physiological alteration promoted by led light

BENEDETTO, MARÍA M.; BRUERA, MANUEL G.; GUENDULAIN, GONZALO G.; CONTÍN, MARÍA A.

Journal of Photochemistry and Photobiology

Elsevier B.V.

Año: 2023 vol. 14

ods are the most sensitive cells to light present in the retina, being therefore responsible for dim light vision. Light photons captured by the retina stimulate rhodopsin, promoting phototransduction mechanisms that end up sending the information to the brain. However, overexposure to light and continuous receptor stimulation may promote retinal damage. Thus, artificial light might have harmful effects on the retina, most particularly in rods. Light‐emitting diodes (LEDs) are nowadays the most used devices, and therefore their potential damage to the visual system should be evaluated and considered as a potential environmental factor in retinal degeneration. Particularly in Wistar rats, tonic receptors stimulation under constant light exposure (LL) produces retinal remodeling, inducing classical photoreceptors death and a re-location of non-classical opsins. This work aims to show the effects of LED devices on rat retinas under intermittent stimulation. Wistar rats were exposed