Agarofuran sesquiterpenes from Schaefferia argentinensis

GARCIA, MANUELA E; MOTRICH, RD; CAPUTTO, BL; SANCHEZ, M; PALERMO, JM; ESTEVEZ BRAUN, ANA; RAVELO, ÁNGEL G.; NICOTRA, VIVIANA E.

PERGAMON-ELSEVIER SCIENCE LTD

Lugar: Amsterdam; Año: 2013 vol. 94 p. 260 - 260

ixteen dihydro-beta-agarofuran sesquiterpenes were isolated from the aerial parts of Schaefferia argentinensis Speg. Their structures were determined by a combination of 1D and 2D NMR and MS techniques. The in vitro antiproliferative activity of the major sesquiterpenes was examined in T47D, MCF7, and MDA-MB231 human cancer cell lines, but was found to be marginal.