Implications of prostate inflammation on male fertility

MOTRICH, RUBEN D.; SALAZAR, FLORENCIA C.; BRESER, MARIA L.; MACKERN-OBERTI, JUAN P.; GODOY, GLORIA J.; OLIVERA, CAROLINA; PAIRA, DANIELA A.; RIVERO, VIRGINIA E.

ANDROLOGIA

WILEY-BLACKWELL PUBLISHING, INC

Lugar: Londres; Año: 2018 p. 1 - 1

0303-4569

he prostate is the seat of three major causes of morbidity: benign prostatic hyperplasia, prostate cancer and prostatitis, three conditions in which inflammation has been implicated. A state of inflammation of the prostate gland, originally incited by an infection, an autoimmune response, a neurogenic stimulus or another trigger may have consequences on prostate functionality. In fact, male fertility depends intrinsically on the content of prostatic fluid factors secreted by the prostatic epithelium. Taking into account that the prostate gland is the major male accessory gland that exerts essential functions for male fertility, a state of local inflammation can alter male fertility by either directly impairing sperm quality or, indirectly, by causing prostate dysfunction. In the present review, we summarize the current knowledge regarding prostatitis due to well-known infections such as Escherichia coli, Chlamydia trachomatis and other commonly identified microorganisms focusing on in