Interferon gamma, IL-17, and IL-1Beta impair sperm motility and viability and induce sperm apoptosis

PAIRA, DANIELA A.; SILVERA-RUIZ, SILENE M.; TISSERA, ANDREA D.; MOLINA, ROSA I.; OLMEDO, JOSE J.; RIVERO, VIRGINIA E.; MOTRICH, RUBEN D.

CYTOKINE.

ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD

Lugar: Amsterdam; Año: 2022 vol. 152

1043-4666

span class="markedContent" id="page238R_mcid1">Urogenital inflammation is a known cause of male infertility. Increased levels of inflammatory cytokines, leukocyte counts and oxidative stress are highly detrimental for sperm quality thus compromising male fertility. Although cytokines affect sperm by recruiting and activating leukocytes consequently inducing tissue inflammation and