Persistent oligonecrozoospermia after asymptomatic SARS-CoV-2 infection. A case report and literature review

PAIRA, DANIELA ANDREA; BELTRAMONE, FERNANDO; OLMEDO, JOSÉ JAVIER; TISSERA, ANDREA DANIELA; MOLINA, ROSA ISABEL; FUX-OTTA, CAROLINA; OLIVERA, CAROLINA; MOTRICH, RUBEN DARIO

Heliyon

Cell Press

Lugar: Cambridge; Año: 2023 vol. 9

2405-8440

OVID-19 is known to have deleterious effects on different systems such as the respiratory, cardiovascular, central nervous, and gastrointestinal. However, conflicting data about the possible implications for male reproductive health and fertility have been reported. In addition, the long-term consequences of SARS-CoV-2 infection remain unclear. Herein, we report a case of a 42-year-old man with no known co-morbidities and normal baseline semen quality, who subsequently suffered an asymptomatic SARS-CoV-2 infection. Shortly after, the patient developed sudden oligoasthenozoospermia, even reaching azoospermia, which gradually evolved into persistent severe oligonecrozoospermia, accompanied by semen inflammation and oxidative stress. Remarkably, the latter occurred in the absence of urogenital infections, hormonal imbalances, tissue/organ obstruction/damage, medication or drug treatment, smoking, or exposure to toxins/pollutants, radiation, or high temperature. This case constitutes valu