Co-thermolysis: An One-Pot Synthetic Method for novel 2-Substitued-5-(trifluoromethoxy) thiophenes

WALTER J. PELÁEZ; GUSTAVO A. ARGÜELLO

PERGAMON-ELSEVIER SCIENCE LTD

Año: 2010 vol. 51 p. 5242 - 5242

span style="FONT-FAMILY: "Helvetica","sans-serif"; FONT-SIZE: 10pt; mso-fareast-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-ansi-language: EN-GB; mso-fareast-language: EN-US; mso-bidi-language: AR-SA" lang="en">Abstract— A new “green” process to obtain trifluoromethoxylated compounds by a gas-phase method has been accomplished. Through it, new 2-substitued-5-(trifluoromethoxy)thiophenes have been obtained from moderate to good yields. Though the reaction occurs in the gas-phase and radicals are involved, an electron transfer mechanism is also postulated to explain the appearance of all detected products.