Highly Efficient Dehydrogenation of 5-Benzyl-3-phenyl-2-thioxoimidazolidin-4-one. Microwave versus Flash Vacuum Pyrolysis Conditions

ANA J. PEPINO; WALTER J. PELÁEZ; E. LAURA MOYANO; GUSTAVO A. ARGÜELLO

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

WILEY-V C H VERLAG GMBH

Lugar: Weinheim; Año: 2012 vol. 2012 p. 3424 - 3424

1099-0690

-Benzyl-3-phenyl-2-thioxoimidazolidin-4-one underwent thermal dehydrogenation to afford 5-benzylidene-2-thioxoimidaxolidin-4-one under microwave and flash vacuum pyrolysis conditions. A high predominance of the Z-isomer over the E-isomer of the imidazolidinone product was achieved. By using DFT and NBO calculations, the mechanism of the dehydrogenation and the selectivity were also explored. ;Flash pyrolysis;Microwave chemistry;Reaction mechanisms