EXPRESIÓN DE MOLÉCULAS DE ADHESIÓN LEUCOCITARIA EN UN PACIENTE CON IDCV?.

MENSO, E.; ROMAGNOLI, P; CRISCUOLO, M; BARCELONA, P; COLLINO C; SERRA H

REVISTA ALERGIA DE MEXICO

Nieto Editores

Lugar: Mexico DF; Año: 2004 vol. 51 p. 13 - 13

Common variable inmunodeficiency is one of main antibody´ deficiency syndromes. Objective: To present the immunological study of a 29-year-old patient with common variable immunodeficiency who assisted to a check-up after beging four year without treatment with gammaglobuline.Material and Methods: We studied a sample of peripheral blood and saliva of patient with common variable immunodeficiency and that of healthy patient (control). Assessment of immunoglobulin G, immunoglobulin A and immunoglobulin M was performed by simple radial immunodiffusion test, and immunoglobulin E by immunoassay. Immunophenotypic study of leucocytic subpopulations was done by citometry by using the following panel pf monoclonal antibodies: CD3 (Leu-4), CD4 (Leu-3a), CD8 (Leu-2a), CD19 (Leu-12), CD14 (Leu-M3), CD11a (LFA-I), CD49d (VLA-4), CD54 (ICAM-1), CD31 (PECAM).Results: It was found a significamt reducction in most of the serum and secretory immunoglobulins, level of unusual expression of inte