COMMON VARIABLE IMMUNODEFICIENCY: RECENT FINDINGS IN CELLULAR ABNORMALITIES.

SERRA H M,; BARCELONA PF; COLLINO C; VETTORAZZI L

ACTA BIOQUíMICA CLíNICA LATINOAMERICANA

Federación Bioquímica de la Prov. de Bs. As.

Lugar: Buenos Aires; Año: 2004 vol. 38 p. 489 - 489

0325-2957

p class="MsoNormal" style="TEXT-JUSTIFY: inter-ideograph; MARGIN: 0cm 0cm 0pt; LINE-HEIGHT: 200%; TEXT-ALIGN: justify">The Common Variable Immunodeficiency (CVID), also well known as acquired hypogammaglobulinemia o disgammaglobulinaemia, is a heterogeneous group of disorders in which T and B lymphocytes are affected. It is one of the most important syndromes of antibodies deficiency characterized by an impaired antigen specific humoral immune response, particularly against bacterial capsular polysaccharides. These patients have a high susceptibility to recurrent infections of the respiratory tract and the CVID has a narrow relationship with pathologies such as deficiency of IgA and IgG subclases.