Atypical regioselective biohydrolysis on steroidal oxiranes by Aspergillus niger whole cells: Some stereochemical features

FABRICIO R. BISOGNO

STEROIDS

ELSEVIER SCIENCE INC

Año: 2007 vol. 72 p. 643 - 643

0039-128X

font size="1" face="Caecilia-Roman"> 5,6-Epoxycholestan-3beta-ol derivatives were hydrolyzed in a diastereoconvergent manner by growing and resting cells of several strains of Aspergillus niger, particularly A. niger ATCC 11394. These strains displayed opposite regioselectivity toward each isomer in an alfa and beta epoxide mixture, thus, the nucleophilic atta