?Asymmetric bioreduction of natural xenobiotic diketones by Brassica napus hairy roots?

FABRICIO R. BISOGNO

JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

ELSEVIER

Año: 2006 vol. 42 p. 71 - 71

1381-1177

p style="TEXT-ALIGN: justify; LINE-HEIGHT: 200%; TEXT-INDENT: 18pt; MARGIN: 0cm 0cm 0pt; BACKGROUND: white" class="MsoNormal"> Enantioselective bioreduction of natural prochiral diketones and some chemical derivatives were mediated by Brassica napus hairy root cultures. The natural diketones 1-(5-acetyl-2-hydroxyphenyl)-3-methylbut-2-en-1-one (1) and 6-acetyl-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one (2) were both transformed into 6-(1(S)-hydroxyethyl)-2,2-dimethyl-2,3-dihydro-4H-chromen-4-one (4) in high enantiomeric excesses (