Synthesis of asymmetrically meso-substituted porphyrins bearing amino groups as potential cationic photodynamic agents.

CAMINOS, D. A.; DURANTINI, E. N.

WORLD SCI PUBL CO INC

Año: 2005 vol. 9 p. 334 - 334

span style="FONT-FAMILY: "Times New Roman","serif"; FONT-SIZE: 11pt; mso-ansi-language: EN-US; mso-fareast-font-family: "Times New Roman"; mso-fareast-language: ES; mso-bidi-language: AR-SA" lang="en">  Novel asymmetrically meso-substituted porphyrins bearing amino groups have been synthesized as precursors of cationic photodynamic agents. The amphiphilic character of these porphyrins was increased by the presence of a high lipophilic trifluoromethyl group. Different patterns of porphyrin structures were obtained from meso-4-[(3-N,N-dimethylaminopropoxy)phenyl] dipyrromethane 1, which was formed by the