Interaction and photodynamic activity of cationic porphyrin derivatives bearing different patterns of charge distribution with GMP and DNA

DANIEL A. CAMINOS; EDGARDO N. DURANTINI

ELSEVIER SCIENCE SA

Año: 2008 vol. 198 p. 274 - 274

font size="1" face="OneGulliverA"> The interaction of amphiphilic cationic porphyrins, containing different patterns of meso-substitution by 4-(3-N,N,N-trimethylammoniumpropoxy)phenyl (A) and 4-(tri.uoromethyl)phenyl (B) groups, with guanosine 5-monophosphate (GMP) and calf thymus DNA have been studied by optical methods in phosphate buffer solution. The properties of these synthetic porphyrins were compared with those of representative standard of anionic 5,10,15,20-tetra(4-sulphonatophenyl)porphyrin (TPPS