Mechanisms of Escherichia coli photodynamic inactivation by a amphiphilic tricationic porphyrin and 5,10,15,20-tetra(4-N,N,N-trimethylammoniumphenyl) porphyrin

DANIEL A. CAMINOS; MARIANA B. SPESIA; PATRICIA PONS; EDGARDO N. DURANTINI

The Royal Society of Chemistry

Lugar: London; Año: 2008 p. 1 - 1

p style="TEXT-ALIGN: justify; LINE-HEIGHT: 200%; TEXT-INDENT: 36pt; MARGIN: 0cm 0cm 0pt" class="MsoNormal">The mechanistic aspects of Escherichia coli photodynamic inactivation (PDI) have been investigated in bacteria treated with 5,10,15-tris[4-(3-N,N,N-trimethylammoniumpropoxy)phenyl]-20-(4-trifluoromethylphenyl)porphyrin iodide (A3B3+) and visible light. The photosensitization activity of A3B3+ porphyrin was compared with that of 5,10,15,20-tetra(4-N,N,N-trimethylammonium phenyl)porphyrin p-tosylate (TMAP4+), which is a standard acti