Personal Blood Glucose Analyzers.

M. EGUÍLAZ, M.D. RUBIANES, M.C. RODRÍGUEZ, F. GUTIERREZ; P. DALMASSO; P. GALLAY, A. MONTEMERLO, M.LÓPEZ MUJICA, F. PERRACHIONE, G.A. RIVAS; MUSTAFA KEMAL SEZGINTÜRK

Commercial Biosensors and Their Applications. Clinical, Food, and Beyond.

Elsevier

Año: 2020; p. 29 - 50

Diabetes mellitus is a metabolic disorder associated with the inability of pancreatic cells to produce insulin or the incapacity of the organism to use their own insulin, characterized by an increment of blood glucose concentration (hyperglycemia). It is a chronic disease where uncontrolled glucose can produce long-term multiorgans damage involving cardiovascular diseases, neuropathy, nephropathy, retinopathy, and blindness among others. However, despite all the health problems produced by diabetes, when the glucose levels are properly controlled, these unhealthy conditions could be prevented or delayed. Therefore, the monitoring of blood glucose level is crucial for the diagnosis and management of diabetes, and in this sense, the decentralized measurement of glucose offers great advantages compared with the classical determinations in the laboratory of clinical analysis.The intense research activity about glucose biosensors performed in the last decades has allowed a significant progress in the development of commercial glucose monitoring systems. Despite the great advances made in this field, there are still many challenges that require attention related to the fast, stable, and reliable glycemia monitoring in a painless, userfriendly, and low-cost way.