Quercetin tetraacetyl derivative inhibits LPS-induced nitric oxide synthase (iNOS) expression in J774.1 cells

M.G. ORTEGA; A.C. SARAGUSTI; J.L. CABRERA; G.A. CHIABRANDO

ELSEVIER SCIENCE INC

Año: 2010 vol. 498 p. 105 - 105

font face="AdvGulliv-R" size="1"> In inflammation, nitric oxide (NO) acts as a pro-inflammatory mediator, which is synthesized by induc- ible nitric oxide synthase (iNOS) in response to pro-inflammatory agents such as lipopolysaccharide (LPS). Quercetin (Qt) has anti-inflammatory properties through its ability to inhibits nitric oxide produc- tion and iNOS expression in different cellula