INHIBITORY EFFECTS OF SULPHATED FLAVONOIDS ISOLATED FROM FLAVERIA BIDENTIS ON PLATELET AGGREGATION

H.GUGLIELMONE, A.M.AGNESE, S.C.NUÑEZ AND J.L.CABRERA.

THROMBOSIS RESEARCH

Elsevier

Lugar: Amsterdam; Año: 2005 vol. 115 p. 495 - 495

0049-3848

font face="AdvTTda6f6cb8.B" size="1"> Abstract Flaveria bidentis is a plant species that has as major constituents sulphated flavonoids in the highest degree of sulphatation. Among them,quercetin 3,7,3V,4V-tetrasulphate (QTS) and quercetin 3-acetyl-7,3V,4V-trisulphate(ATS) are the most important constituents. Both showed anticoagulant properties. The objective of the present study was to evaluate the effects of theseflavonoids on human platelet aggregation in comparison with the well-known inhibitor quercetin (Qc) by using severa