ABSTRACT
Studies undertaken on isolated photosensitizing
agents from Heterophyllaea pustulata, a phototoxic
plant, which natural habitat is the Northwestern part of Argentina, are presented here. The carried out work involved several steps that were initiated with the chemical-structural study of their most important secondary metabolites. As a result, three flavonoids, one iridoid glycoside (asperuloside) and ten aglycone anthraquinones were identified. Through the study of the photophysical, photochemical and photo-biological properties of the anthraquinone derivatives, we concluded that they show good photosensitizing (type I and type II) characteristics. The performed toxicological assays in vivo showed a direct
cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
plant, which natural habitat is the Northwestern
part of Argentina, are presented here. The
carried out work involved several steps that were
initiated with the chemical-structural study of
their most important secondary metabolites. As a
result, three flavonoids, one iridoid glycoside
(asperuloside) and ten aglycone anthraquinones
were identified. Through the study of the photophysical,
photochemical and photo-biological
properties of the anthraquinone derivatives, we
concluded that they show good photosensitizing
(type I and type II) characteristics. The performed
toxicological assays in vivo showed a direct
cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
plant, which natural habitat is the Northwestern
part of Argentina, are presented here. The
carried out work involved several steps that were
initiated with the chemical-structural study of
their most important secondary metabolites. As a
result, three flavonoids, one iridoid glycoside
(asperuloside) and ten aglycone anthraquinones
were identified. Through the study of the photophysical,
photochemical and photo-biological
properties of the anthraquinone derivatives, we
concluded that they show good photosensitizing
(type I and type II) characteristics. The performed
toxicological assays in vivo showed a direct
cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
plant, which natural habitat is the Northwestern
part of Argentina, are presented here. The
carried out work involved several steps that were
initiated with the chemical-structural study of
their most important secondary metabolites. As a
result, three flavonoids, one iridoid glycoside
(asperuloside) and ten aglycone anthraquinones
were identified. Through the study of the photophysical,
photochemical and photo-biological
properties of the anthraquinone derivatives, we
concluded that they show good photosensitizing
(type I and type II) characteristics. The performed
toxicological assays in vivo showed a direct
cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
plant, which natural habitat is the Northwestern
part of Argentina, are presented here. The
carried out work involved several steps that were
initiated with the chemical-structural study of
their most important secondary metabolites. As a
result, three flavonoids, one iridoid glycoside
(asperuloside) and ten aglycone anthraquinones
were identified. Through the study of the photophysical,
photochemical and photo-biological
properties of the anthraquinone derivatives, we
concluded that they show good photosensitizing
(type I and type II) characteristics. The performed
toxicological assays in vivo showed a direct
cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Heterophyllaea pustulata, a phototoxicplant, which natural habitat is the Northwestern
part of Argentina, are presented here. The
carried out work involved several steps that were
initiated with the chemical-structural study of
their most important secondary metabolites. As a
result, three flavonoids, one iridoid glycoside
(asperuloside) and ten aglycone anthraquinones
were identified. Through the study of the photophysical,
photochemical and photo-biological
properties of the anthraquinone derivatives, we
concluded that they show good photosensitizing
(type I and type II) characteristics. The performed
toxicological assays in vivo showed a direct
cause-effect relation between these metabolites and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given. Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
cause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
in vivo showed a directcause-effect relation between these metabolites
and the reported phototoxicity for H. pustulata.
Finally, a few words about the potential application of these photsensitizing compounds as antibacterial agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.
H. pustulata.Finally, a few words about the potential application
of these photsensitizing compounds as antibacterial
agents will be given.