NICOLA, JP

Sodium iodide symporter-targeted gene therapy in glioblastoma

Mol Ther Oncolytics; Año: 2023 vol. 28 p. 44 - 45

NICOLA, JP

Combined Vorinostat and Chloroquine Inhibit Sodium Iodide Symporter Endocytosis and Enhance Radionuclide Uptake In Vivo

CLINICAL CANCER RESEARCH; Año: 2023

NICOLA, JP

MOLECULAR MECHANISMS UNDERLYING SODIUM IODIDE SYMPORTER EXPRESSION AT THE PLASMA MEMBRANE IN THE THYROID FOLLICULAR CELL

Current Opinion in Endocrine and Metabolic Research; Año: 2023

BERNAL BARQUERO, CE; MARTIN, M; GEYSELS, RC; PEYRET, V; PAPENDIECK, P; MASINI-REPISO, AM; CHIESA, AE; NICOLA, JP

An intramolecular ionic interaction linking defective sodium/iodide symporter transport to the plasma membrane and dyshormonogenic congenital hypothyroidism

THYROID; Lugar: New York; Año: 2022

MARTIN, M; BRUNELLO, FG; MODENUTTI, CP; NICOLA, JP; MARTI, MA

MotSASi: Functional short linear motifs (SLiMs) prediction based on genomic single nucleotide variants and structural data

BIOCHIMIE; Lugar: Paris; Año: 2022 vol. 197 p. 59 - 73

GEYSELS, RC; BERNAL BARQUERO, CE; MARTIN, M; PEYRET, V; SOBRERO, G; MUÑOZ, L; SIGNORINO, M; TESTA, G; CASTRO, RB; MASINI-REPISO AM; MIRAS, M; NICOLA, JP

Silent but not harmless: A synonymous SLC5A5 gene variant leading to dyshormonogenic congenital hypothyroidism

FRONTIERS IN ENDOCRINOLOGY; Año: 2022

DI GIUSTO, P; MARTIN, M; FUNES CHABÁN, M; SAMPIERI, L; NICOLA, JP; ALVAREZ, CI

Transcription Factor CREB3L1 Regulates the Expression of the Sodium/Iodide Symporter (NIS) in Rat Thyroid Follicular Cells

CELLS (BASEL); Año: 2022

BERNAL BARQUERO, CE; GEYSELS, RC; JACQUES, V; CARRO, GH; MARTIN, M; PEYRET, V; ABREGÚ, MC; PAPENDIECK, P; MASINI-REPISO, AM; SAVAGNER, F; CHIESA, AE; CITTERIO, CE; NICOLA, JP

Targeted Next-Generation Sequencing of Congenital Hypothyroidism-causative Genes Reveals Unexpected Thyroglobulin Gene Variants in Patients with Iodide Transport Defect

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; Lugar: Basel; Año: 2022 vol. 23

NICOLA, JP

Structural insights into the mechanism of the sodium/iodide symporter (NIS)

NATURE; Lugar: Londres; Año: 2022

GEYSELS, RC; PEYRET, V; MARTI, M; NAZAR, M; REALE, C; BERNAL BARQUERO, CE; MIRANDA, L; MARTI, MA; VITO, P; MASINI-REPISO AM; NICOLA, JP

The transcription factor NF-kB mediates thyrotropin-stimulated expression of thyroid differentiation markers

THYROID; Lugar: New York; Año: 2021 vol. 31 p. 299 - 314

MARTIN, M; SALLERON, L; PEYRET, V; GEYSELS, RC; DARROUZET, E; LINDENTHAL, S; BERNAL BARQUERO, CE; MASINI-REPISO, AM; POURCHER, T; NICOLA, JP

The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane

FASEB JOURNAL; Lugar: Bethesda; Año: 2021

MARTÍN, MARIANO; MODENUTTI, CARLOS PABLO; GIL ROSAS, MAUCO LUCAS; PEYRET, VICTORIA; GEYSELS, ROMINA CELESTE; BERNAL BARQUERO, CARLOS EDUARDO; SOBRERO, GABRIELA; MUÑOZ, LILIANA; SIGNORINO, MALVINA; TESTA, GRACIELA; MIRAS, MIRTA BEATRIZ; MASINI-REPISO, ANA MARÍA; CALCATERRA, NORA BEATRIZ; COUX, GABRIELA; CARRASCO, NANCY; MARTÍ, MARCELO ADRIÁN; NICOLA, JUAN PABLO

A Novel SLC5A5 Variant Reveals the Crucial Role of Kinesin Light Chain 2 in Thyroid Hormonogenesis

The Journal of clinical endocrinology and metabolism; Año: 2021 vol. 106 p. 1867 - 1881

MARTÍN, MARIANO; NICOLA, JUAN PABLO

Impact of the mutational landscape of the sodium/iodide symporter in congenital hypothyroidism

THYROID; Año: 2021

STEMPIN, CINTHIA CAROLINA; GEYSELS, ROMINA CELESTE; PARK, SUNMI; PALACIOS, LUZ MARIA; VOLPINI, XIMENA; MOTRAN, CLAUDIA CRISTINA; RODRÍGUEZ, EVA VIRGINIA ACOSTA; NICOLA, JUAN PABLO; CHENG, SHEUE-YANN; PELLIZAS, CLAUDIA GABRIELA; FOZZATTI, LAURA

Secreted factors by anaplastic thyroid cancer cells induce tumor-promoting m2-like macrophage polarization through a tim3-dependent mechanism

Cancers; Año: 2021 vol. 13

GARCÍA, LUCIANA NOEMI; LEIMGRUBER, CAROLINA; NICOLA, JUAN PABLO; QUINTAR, AMADO ALFREDO; MALDONADO, CRISTINA ALICIA

Neonatal endotoxin stimulation is associated with a long-term bronchiolar epithelial expression of innate immune and anti-allergic markers that attenuates the allergic response

PLOS ONE; Año: 2020 vol. 15

MARTÍN, MARIANO; MODENUTTI, CARLOS PABLO; PEYRET, VICTORIA; GEYSELS, ROMINA CELESTE; DARROUZET, ELISABETH; POURCHER, THIERRY; MASINI-REPISO, ANA MARÍA; MARTÍ, MARCELO ADRIÁN; CARRASCO, NANCY; NICOLA, JUAN PABLO

A Carboxy-Terminal Monoleucine-Based Motif Participates in the Basolateral Targeting of the Na+/I– Symporter (NIS)

ENDOCRINOLOGY; Año: 2019 vol. 160 p. 156 - 168

MARTÍN, MARIANO; GEYSELS, ROMINA CELESTE; PEYRET, VICTORIA; BERNAL BARQUERO, CARLOS EDUARDO; MASINI-REPISO, ANA MARÍA; NICOLA, JUAN PABLO

Implications of Na+/I- Symporter Transport to the Plasma Membrane for Thyroid Hormonogenesis and Radioiodide Therapy

Journal of the Endocrine Society; Año: 2019 vol. 3 p. 222 - 234

MARTIN, M; BERNAL BARQUERO, CE; GEYSELS, RC; PAPENDIECK, P; PEYRET, V; MASINI-REPISO, AM; CHIESA, AE; NICOLA, JP

Novel Sodium/Iodide Symporter Compound Heterozygous Pathogenic Variants Causing Dyshormonogenic Congenital Hypothyroidism

THYROID; Año: 2019

NICOLA, JUAN P.

Inefficient N2-Like Neutrophils Are Promoted by Androgens During Infection

Frontiers in Immunology; Año: 2018 vol. 9

SOSA, LILIANA DEL V; PETITI, JUAN P; PICECH, FLORENCIA; CHUMPEN, SABRINA; NICOLA, JUAN P; PEREZ, PABLO; DE PAUL, ANA; VALDEZ-TAUBAS, JAVIER; GUTIERREZ, SILVINA; TORRES, ALICIA I

The ERalpha membrane pool modulates the proliferation of pituitary tumours

JOURNAL OF ENDOCRINOLOGY; Año: 2018

PEINETTI, NAHUEL; SCALERANDI, MARÍA VICTORIA; CUELLO RUBIO, MARIANA MICAELA; LEIMGRUBER, CAROLINA; NICOLA, JUAN PABLO; TORRES, ALICIA INES; QUINTAR, AMADO ALFREDO; MALDONADO, CRISTINA ALICIA

The Response of Prostate Smooth Muscle Cells to Testosterone Is Determined by the Subcellular Distribution of the Androgen Receptor

ENDOCRINOLOGY; Año: 2018 vol. 159 p. 945 - 956

PEYRET, VICTORIA; NAZAR, MAGALÍ; MARTÍN, MARIANO; QUINTAR, AMADO A.; FERNANDEZ, ELMER A.; GEYSELS, ROMINA C.; FUZIWARA, CESAR S.; MONTESINOS, MARÍA M.; MALDONADO, CRISTINA A.; SANTISTEBAN, PILAR; KIMURA, EDNA T.; PELLIZAS, CLAUDIA G.; NICOLA, JUAN P.; MASINI-REPISO, ANA M.

Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK–Induced ETS1 Transcriptional Activity

MOLECULAR CANCER RESEARCH; Año: 2018 vol. 16 p. 833 - 845

NICOLA, JP

Clinical Relevance of Molecular Diagnosis in Patients with Congenital Hypothyroidism

Journal of Molecular and Genetic Medicine; Año: 2017 vol. 11

LEIMGRUBER, CAROLINA; QUINTAR, AMADO A.; PEINETTI, NAHUEL; SCALERANDI, MARÍA V.; NICOLA, JUAN P.; MIANO, JOSEPH M.; MALDONADO, CRISTINA A.

Testosterone Rescues the De-Differentiation of Smooth Muscle Cells Through Serum Response Factor/Myocardin

JOURNAL OF CELLULAR PHYSIOLOGY; Año: 2017 vol. 232 p. 2806 - 2817

MONTESINOS, MM; NICOLA, JP; NAZAR, M; PEYRET, V; LUCERO, AM; PELLIZAS, CG; MASINI-REPISO, AM

Nitric Oxide-Repressed Forkhead Factor FOXE1 Expression is Involved in the Inhibiton of TSH-Induced Thyroid Peroxidase Levels

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2016 vol. 420 p. 105 - 115

SERRANO-NASCIMENTO, C; NICOLA, JP; CALIL-SILVEIRA, J; POYARES, LL; LELLIS-SANTOS, C; BORDIN, S; MASINI-REPISO, AM; NUNEZ, MT

Excess iodide downregulates Na+/I- symporter gene transcription through activation of PI3K/Akt pathway

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2016 vol. 426 p. 73 - 90

MARTIN, M; NICOLA, JP

Congenital Iodide Transport Defect: Recent Advances and Future Perspectives

J Clin Mol Encodrinol; Año: 2016

NICOLA, JP; MASINI-REPISO, AM

Emerging Therapeutics for Radioiodide-Refractory Thyroid Cancer

Journal of Analytical Oncology; Lugar: Mississauga; Año: 2016 vol. 5 p. 75 - 86

FERRANDINO, G; NICOLA, JP; SÁNCHEZ, YE; ECHEVERRIA, I; LIU, Y; AMZEL, LM; CARRASCO, N

Na+ coordination at the Na2 site of the Na+/I- symporter

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2016 vol. 113 p. 5379 - 5388

ROSSICH, LE; THOMASZ, L; NICOLA, JP; NAZAR, M; SALVARREDI, L; PISAREV, MA; MASINI-REPISO, AM; CHRISTOPHE-HOBERTUS, C; CHRISTOPHE, D; JUVENAL, GJ

Effects of 2-iodohexadecanal in the physiology of thyroid cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2016 vol. 437 p. 292 - 301

VACA, AM; GUIDO, CB; SOSA, LV; NICOLA, JP; MUKDSI, J; PETITI, JP; TORRES, AI

The expansion of adult stem/progenitor cells and their marker expression fluctuations are linked with pituitary plastic adaptation during gestation and lactancy

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM; Lugar: Bethesda; Año: 2016 vol. 311 p. 367 - 379

RAVERA, S; QUICK, M; NICOLA, JP; CARRASCO, N; AMZEL, LM

Beyond non-integer Hill coefficients: A novel approach to analyzing binding data, applied to Na+-driven transporters.

Lugar: New York; Año: 2015 vol. 145 p. 555 - 563

NICOLA, JP; CARRASCO, N; MASINI-REPISO, AM

Dietary I(-) absorption: expression and regulation of the Na(+)/I(-) symporter in the intestine

Lugar: Burlington, MA, Estados Unidos; Año: 2015 vol. 98 p. 1 - 31

NICOLA, JP; REYNA-NEYRA, A; SAENGER, P; RODRIGUEZ-BURITICA, DF; GAMEZ GODOY, JD; MUZUMDAR, R; AMZEL, LM; CARRASCO, N

The sodium/iodide symporter mutant V270E causes stunted growth but no cognitive deficiency

Lugar: Washington; Año: 2015 vol. 100 p. 1353 - 1361

NICOLA, JP; PEYRET, V; NAZAR, M; ROMERO, JM; LUCERO, AM; MONTESINOS, MM; BOCCO, JL; PELLIZAS, CG; MASINI-REPISO, AM

S-nitrosylation of NF-kB p65 inhibits TSH-induced Na+/I- symporter expression

Lugar: Washington; Año: 2015 vol. 156 p. 4741 - 4751

MONTESINOS, MM; NICOLA, JP; NAZAR, M; PEYRET, V; LUCERO, AM; PELLIZAS, CG; MASINI-REPISO, AM

Nitric Oxide-Repressed Forkhead Factor FOXE1 Expression is Involved in the Inhibiton of TSH-Induced Thyroid Peroxidase Levels

Lugar: Amsterdam; Año: 2015

SERRANO-NASCIMENTO, C; DA SILVA TEIXEIRA, ; NICOLA, JP; NACHBAR, RT; CURI, R; MASINI-REPISO, AM; NUNEZ, MT

The acute inhibitory effects of iodide excess on sodium/iodide symporter expression and activity involve the PI3K/Akt signaling pathway

Año: 2014 vol. 155 p. 1145 - 1156

NICOLA, JP; CARRASCO, N; AMZEL, LM

Physiological sodium concentrations enhance the iodide affinity of the Na+/I- symporter (NIS)

Año: 2014 vol. 5 p. 1 - 10

LI, W.; NICOLA, JP; AMZEL, LM; CARRASCO, N

Asn441 plays a key role in folding and function of the Na+/I- symporter (NIS)

Lugar: Bethesda; Año: 2013 vol. 27 p. 3229 - 3238

PARODER, V; NICOLA, JP; GINTER, CS; CARRASCO, N

The iodide-transport-defect-causing mutation R124H: a δ-amino group at position 124 is critical for maturation and trafficking of the Na+/I- symporter.

Lugar: Cambridge; Año: 2013 vol. 126 p. 3305 - 3313

NICOLA, JP; REYNA-NEYRA, A; CARRASCO, N; MASINI-REPISO, AM

Dietary iodide controls its own absorption through post-transcriptional regulation of the intestinal Na+/I- symporter.

Lugar: Londres; Año: 2012 vol. 590 p. 6013 - 6026

PURTELL, K; PARODER-BELENITSKY, M; REYNA-NEYRA, A; NICOLA, JP; KOBA, W; FINE, E; CARRASCO, N; ABOOTT, GW

The KCNQ1-KCNE2 K+ channel is required for adequate thyroid I- uptake

Lugar: Bethesda; Año: 2012 vol. 26 p. 3252 - 3259

NAZAR, M; NICOLA, JP; VÉLEZ, ML; PELLIZAS, CG; MASINI-REPISO, AM

Thyroid peroxidase gene expression is induced by lipopolysaccharide involving nuclear factor (NF)-κB p65 subunit phosphorylation.

Año: 2012 vol. 153 p. 6114 - 6125

PARODER, M; MAESTRAS, M; DOHAN, O; NICOLA, JP; REYNA-NEYRA, A; FOLLENZI, A; DADACHOVA, E; ESKANDARI, S; AMZEL, LM; CARRASCO, N

Mechanism of anion selectivity and stoichiometry of the Na+/I- symporter (NIS)

Lugar: Washington DC, USA; Año: 2011 vol. 108 p. 17933 - 17938

NICOLA, JP; NAZAR, M; SERRANO-NASCIMENTO, C; GOULART-SILVA, F; SOBRERO, G; TESTA, G; NUNEZ, MT; MUÑOZ, L; MIRAS, M; MASINI-REPISO, AM

Iodide transport defect: functional characterization of a novel mutation in the Na+/I- symporter 5'-untranslated region in a patient with congenital hypothyroidism

Año: 2011 vol. 96 p. 1100 - 1107

NICOLA, JP; NAZAR, M; MASCANFRONI, I; PELLIZAS, CG; MASINI-REPISO, AM

NF-kappaB p65 subunit mediates lipopolysaccharide-induced Na+/I- symporter gene expression by involving functional interaction with the paired domain transcription factor PAX8

Año: 2010 vol. 24 p. 1846 - 1862

MASCANFRONI, ID; MONTESINOS, MM; ALAMINO, VA; SUSPERREGUY, S; NICOLA, JP; ILARREGUI, JM; MASINI-REPISO, AM; RABINOVICH, GA; PELLIZAS, CG

Nuclear factor (NF)-kB-dependent thyroid hormone receptor β1-expression controls dendritic cell function via AKT signaling

Lugar: Bethesda, Maryland; Año: 2010 vol. 285 p. 9569 - 9582

NICOLA JP; VELEZ ML; LUCERO AM; FOZZATTI L; PELLIZAS CG; MASINI-REPISO AM

Toll-like receptor 4 confering lipopolysaccharide responsiveness is expressed in the thyroid cell

Lugar: Chevy Chase, MD, USA; Año: 2009 vol. 150 p. 500 - 508

NICOLA, JP; BASQUIN, C; PORTULANO, C; REYNA-NEYRA, A; PARODER, M; CARRASCO, N

The Na+/I- symporter (NIS) mediates active iodide uptake in the intestine

Lugar: Bethesda; Año: 2009 vol. 296 p. 654 - 662

GATTI, G; QUINTAR, A; ANDREANI, V; NICOLA, JP; MALDONADO, C; MASINI-REPISO AM; RIVERO, V; MACCIONI, M

Expression of Toll-like receptor 4 in the prostate gland and its association with the severity of prostate cancer

Lugar: New York; Año: 2009 vol. 69 p. 1387 - 1397

FOZZATTI L; VÉLEZ ML; LUCERO AM; NICOLA JP; MACCIÓ DR; PELLIZAS CG; ROTH GA; MASINI-REPISO AM

Endogenous thyrocyte-produced nitric oxide inhibits iodide uptake and thyroid-specific gene expression in FRTL-5 thyroid cells

Lugar: Bristol, UK; Año: 2007 vol. 192 p. 627 - 637