Hydrophilic antioxidants from Andean tomato landraces assessed by their bioactivities in vitro and in vivo

ROMINA D. DI PAOLA NARANJO; SANTIAGO OTAIZA; ALEJANDRA C. SARAGUSTI; VERONICA BARONI; ANDREA DEL V. CARRANZA; IRIS E. PERALTA; ESTELA M. VALLE; FERNANDO CARRARI; RAMÓN ASIS

FOOD CHEMISTRY

ELSEVIER SCI LTD

Lugar: Amsterdam; Año: 2016 vol. 206 p. 146 - 146

0308-8146

otential nutraceutical properties of hydrophilic antioxidants in fruits of tomato landraces collected inAndean valleys were characterised. Antioxidant metabolites were measured by HPLC?DAD?MS/MS inmature fruits and their biological activities were assessed by in vitro and in vivo methods. In vitro antioxidantcapacities were established by TEAC and FRAP methods. For in vivo biological activities we used aprocedure based on Caenorhabditis elegans subjected to thermal stress. In addition, Saccharomyces cerevisiaewas also used as a rapid screening system to evaluate tomato antioxidant capacity. All tomatoaccessions displayed significant differences regarding metabolic composition, biological activity andantioxidant capacity. Metabolite composition was associated with geographical origin and fruit size.Antioxidant activities showed significant association with phenolic compounds, such as caffeoylquinicacids, ferulic acid-O-hexosides and rutin. Combination of in vitro and in vivo methods ap