MRSA dynamic circulation between the community and the hospital setting: new insights from a cohort study in Argentina

DANILO BARCUDI; EZEQUIEL SOSA; RICARDO LAMBERGHINI; ANALÍA GARNERO; DARIO TOSORONI; LAURA DECCA; LILIANA GONZALEZ; MARÍA KUYUK; TERESA LOPEZ; IVANA HERRERO; PAULO CORTES; MYRIAN FIGUEROA; ANA L EGEA; PAULA GAGETTI; DARIO A FERNANDEZ DO PORTO; STUDY GROUP OF S. AUREUS IN CÓRDOBA, ARGENTINA; ALEJANDRA CORSO; ADRIÁN G. TURJANSKI; JOSÉ L. BOCCO; CLAUDIA SOLA

THE JOURNAL OF INFECTION.

W B SAUNDERS CO LTD

Lugar: Londres; Año: 2019

0163-4453

issemination of methicillin-resistant-Staphylococcus aureus/(MRSA) is a worldwideconcern both in hospitals [healthcare-associated-(HA)-MRSA] and communities[community-associated-(CA)-MRSA]. Knowledge on when and where MRSAcolonization is acquired and what clones are involved is necessary, to focus efforts for prevention of hospital-acquired MRSA-infections.A prospective/longitudinal cohort study was performed in eight Argentina hospitals(Cordoba/October-December/2014). Surveillance cultures for MRSA (nose-throatinguinal) were obtained on admission and at discharge. MRSA strains were genetically typed as CA-MRSAG and HA-MRSAG genotypes.Overall, 1419 patients were screened and 534 stayed at hospital for > 3 days. S. aureus admission prevalence was 30.9% and 4.2% for MRSA. Overall MRSA acquisition ratewas 2.3/1000 patient-days-at-risk with a MRSA acquisition prevalence of 1.96%(95%CI: 1.0%-3.4%); 3.2% of patients were discharged back to community withMRSA. CA-MRSAG accounted for 84.6% of