SYNTHESIS AND CHARACTERIZATION OF WATER-SOLUBLE DENDRONIZED CHITOSAN USING NEWKOME-TYPE DENDRONS

RIMONDINO, GUIDO NOÉ; STRUMIA, MIRIAM CRISTINA; MARTINELLI, MARISA

ACS Sustainable Chemistry & Engineering

AMERICAN CHEMISTRY SOCIETY

Lugar: WASHINGTON; Año: 2014 vol. 2 p. 2582 - 2582

ith increasing emphasis on environmental care and use of renewable resources, simple and eff ective dendroniza-tion processes were performed to obtain chitosan derivatives. We present diff erent alternatives for the modifi cation of chitosan: dendronization with a biocompatible dendron; a quaternization process with an ammonium salt, which confers a permanent positive charge to the polymer; and a combination of method-ol ogi es all owing amp hiphi lic po lymers. Thi s pro cess conf ers unique multivalent properties to the native chitosan, and further modi fications reach multivalent water-soluble polymers. Hence, the most important highlight of this work is the use of renewable natural polymers and the diff erent methodologies applied to nontoxic solvents with low temperatures. The process described in this paper represents a sustainable alternative for obtaining a functionalized material with properties suitable for application in di fferent areas, such as biomedicine or e